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Article

Altering membrane topology with Sar1 does not impair spindle assembly in Xenopus egg extracts.

Cytoskeleton (Hoboken, N.J.) - 1 Aug 2012

Riggs Blake, Bergman Zane J, Heald Rebecca

Abstract excerpt

Intracellular membrane networks including the endoplasmic reticulum (ER) and the Golgi apparatus experience dramatic reorganization upon entry into mitosis. However, the mechanisms driving these rearrangements and their importance for cell division are poorly understood. The GTPase Sar1 is a component of the secretory pathway and a key activator of anterograde transport of cargo from the ER to the Golgi. Here we...

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Identifiers

PMID: 22605651
DOI: 10.1002/cm.21036
PMCID: PMC3661297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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