Article
Evidence for prebudding arrest of ER export in animal cell mitosis and its role in generating Golgi partitioning intermediates.
Traffic (Copenhagen, Denmark) - 1 May 2001
Prescott A R, Farmaki T, Thomson C, James J, Paccaud J P, Tang B L, Hong W, Quinn M, Ponnambalam S, Lucocq J
Abstract excerpt
During mitosis the interconnected Golgi complex of animal cells breaks down to produce both finely dispersed elements and discrete vesiculotubular structures. The endoplasmic reticulum (ER) plays a controversial role in generating these partitioning intermediates and here we highlight the importa...
Topics
- COP-Coated Vesicles
- Endoplasmic Reticulum
- Golgi Apparatus
- Guanosine Diphosphate
- Guanosine Triphosphate
- HeLa Cells
- Humans
- Microinjections
- Microscopy, Electron
- Microscopy, Fluorescence
- Mitosis
- Monomeric GTP-Binding Proteins
- Mutation
- Saccharomyces cerevisiae Proteins