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Amyloid-β fibril disruption by C60—molecular guidance for rational drug design

1 Jan 2012

Abstract excerpt

The WHO has listed Alzheimer's disease among the major neurological disorders with an estimated 35 million people affected worldwide. Amyloid-β is mostly believed to be the causative factor in Alzheimer's disease and the severity of the disease correlates with the tendency of amyloid-β to form aggregation patterns-plaques. Lacking effective medication, the identification of any underlying mechanistic principles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22596218
DOI: 10.1039/c2cp40680b

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