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Article

The function and pathogenic mechanism of filamin A.

Gene - 5 Jun 2021

Zhou Jie, Kang Xinmei, An Hanxiang, Lv Yun, Liu Xin

Abstract excerpt

Filamin A(FLNa) is an actin-binding protein, which participates in the formation of the cytoskeleton, anchors a variety of proteins in the cytoskeleton and regulates cell adhesion and migration. It is involved in signal transduction, cell proliferation and differentiation, pseudopodia formation, vesicle transport, tumor resistance and genetic diseases by binding with interacting proteins. In order to fully...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33737122
DOI: 10.1016/j.gene.2021.145575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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