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Article

A sweet spot in the FGFR signal transduction pathway.

Science signaling - 17 Jan 2012

Ghabrial Amin S

Abstract excerpt

The hexosamine biosynthetic pathway, whose end product is UDP-N acetylglucosamine (UDP-GlcNAc), lies at the base of cellular glycosylation pathways, including glycosylation of lipids, formation of heparin sulfated proteoglycans, and N- and O-linked glycosylation of proteins. Forward genetic studies in Drosophila have revealed that mutations in genes encoding different enzymes of the hexosamine biosynthetic...

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Share to Drosophila
Share to Fibroblast Growth Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Fibroblast Growth Factor

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Source

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Identifiers

PMID: 22253260
DOI: 10.1126/scisignal.2002789
PMCID: PMC3362922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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