Article
Phenotypic plasticity of grafted catecholaminergic cells in the dopamine-depleted caudate nucleus in the rat.
Neuroscience research. Supplement : the official journal of the Japan Neuroscience Society - 1 Jan 1990
Nishino H, Hashitani T, Kumazaki M
Abstract excerpt
Catecholamine-producing cells were grafted in the caudate nucleus of model rats with hemi-Parkinson's disease--animals with unilateral 6-hydroxydopamine (6-OHDA) lesions in the nigrostriatal dopaminergic pathway. Survival of the grafted cells, dopamine synthesis/release, and recovery from motor i...
Topics
- Adrenal Medulla
- Animals
- Brain Tissue Transplantation
- Catecholamines
- Caudate Nucleus
- Cell Survival
- Dialysis
- Dopamine
- Extracellular Space
- Motor Activity
- Neuronal Plasticity
- Neurons
- Phenotype
- Rats
- Rats, Inbred Strains
