Article
A comparison of the developing dopamine neuron phenotype in cultures of embryonic rat mesencephalon and hypothalamus.
Neurochemistry international - 1 Oct 1994
Kapatos G, Hirayama K
Abstract excerpt
Development of the dopamine (DA) neuron phenotype was monitored in cultures of embryonic rat mesencephalon (MES) and hypothalamus (HYP) maintained for 1 to 21 days in vitro (DIV) in the absence of glial support cells. Cell counts following immunohistochemistry for tyrosine hydroxylase (TH) demonstrated that the number of DA neurons declined by 85% in MES cultures yet increased 5-fold in cultures of HYP, so that...
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