A comparison of the developing dopamine neuron phenotype in cultures of embryonic rat mesencephalon and hypothalamus.

doi:10.1016/0197-0186(94)90137-6

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Article

A comparison of the developing dopamine neuron phenotype in cultures of embryonic rat mesencephalon and hypothalamus.

Neurochemistry international - 1 Oct 1994

Kapatos G, Hirayama K

Abstract excerpt

Development of the dopamine (DA) neuron phenotype was monitored in cultures of embryonic rat mesencephalon (MES) and hypothalamus (HYP) maintained for 1 to 21 days in vitro (DIV) in the absence of glial support cells. Cell counts following immunohistochemistry for tyrosine hydroxylase (TH) demonstrated that the number of DA neurons declined by 85% in MES cultures yet increased 5-fold in cultures of HYP, so that...

Topics

1-Methyl-4-phenylpyridinium
Animals
Axons
Biopterins
Cell Count
Cells, Cultured
Dendrites
Dopamine
Fluorescent Antibody Technique
Hypothalamus
Mesencephalon
Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neurons

Phenotype

RNA, Messenger

Rats

Time Factors

Tyrosine 3-Monooxygenase

Source

Open in PubMed

Identifiers

PMID: 7820064
DOI: 10.1016/0197-0186(94)90137-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7820064-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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