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Article

Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Sept 2012

Lee Young Ho, Choi Sung Jae, Ji Jong Dae, Song Gwan Gyu

Abstract excerpt

OBJECTIVE: The aim of this study was to determine whether phox homology domain containing serine/threonine kinase (PXK) and tyrosine kinase 2 (TYK2) confer susceptibility to systemic lupus erythematosus (SLE). MATERIALS AND METHODS: The authors conducted meta-analyses on associations between SLE susceptibility and the rs6445975 polymorphism of PXK and the rs2304256, rs12720270, rs280519, and rs1272036...

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Share to Case-Control Studies
Share to Intracellular Signaling Peptides and Proteins
Share to Lupus Erythematosus, Systemic
Share to Nerve Tissue Proteins
Share to Polymorphism, Genetic
Share to Protein Serine-Threonine Kinases
Share to TYK2 Kinase
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Source

Identifiers

PMID: 22592861
DOI: 10.1007/s00011-012-0486-y

Genes

PXK
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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