Article
Associations between PTPN22 and TLR9 polymorphisms and systemic lupus erythematosus: a comprehensive meta-analysis.
Archives of dermatological research - 1 Aug 2017
Hu Li-Ya, Cheng Zhi, Zhang Bo, Yin Qiong, Zhu Xiao-Wei, Zhao Pian-Pian, Han Ming-Yu, Wang Xiao-Bo, Zheng Hou-Feng
Abstract excerpt
Previous studies have explored the relationship of PTPN22 and TLR9 polymorphisms with systemic lupus erythematosus (SLE). In consideration of the population stratification, conflicting results and updating data, we conducted a comprehensive meta-analysis, which consists of a total of 17 research articles (9120 cases and 11,724 controls) for PTPN22 and 20 articles (including up to 2808 cases and 3386 controls) for...
Topics
- Black People
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Lupus Erythematosus, Systemic
- Polymorphism, Single Nucleotide
- Protein Tyrosine Phosphatase, Non-Receptor Type 22
- Risk Factors
- Toll-Like Receptor 9
