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Article

Association of polymorphisms across the tyrosine kinase gene, TYK2 in UK SLE families.

Rheumatology (Oxford, England) - 1 Jun 2007

Cunninghame Graham D S, Akil M, Vyse T J

Abstract excerpt

OBJECTIVES: This is a family-based association study to investigate the genetic contribution of tyrosine kinase 2 (TYK2 ) to disease susceptibility in 380 UK systemic lupus erythematosus (SLE) families, consisting of parents and affected offspring. METHODS: Genotyping was performed using the Sequenom platform on DNA from affected individuals and their parents. Haplotypes were constructed using Haploview from the...

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Source

Identifiers

PMID: 17384181
DOI: 10.1093/rheumatology/kel449

Genes

TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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