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Article

The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriers.

PloS one - 1 Jan 2012

Paré Adam, Kim Myungjin, Juarez Michelle T, Brody Stuart, McGinnis William

Abstract excerpt

The Grainy head (GRH) family of transcription factors are crucial for the development and repair of epidermal barriers in all animals in which they have been studied. This is a high-level functional conservation, as the known structural and enzymatic genes regulated by GRH proteins differ between species depending on the type of epidermal barrier being formed. Interestingly, members of the CP2 superfamily of...

Topics

Alleles
Animals
Drosophila Proteins
Drosophila melanogaster
Evolution, Molecular
Fungal Proteins
Mutation
Neurospora
Transcription Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22590528
DOI: 10.1371/journal.pone.0036254
PMCID: PMC3348937

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