Article
Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis.
Journal of cell science - 15 Mar 2008
Narasimha Maithreyi, Uv Anne, Krejci Alena, Brown Nicholas H, Bray Sarah J
Abstract excerpt
Transcription factors of the Grainy head (Grh) family are required in epithelia to generate the impermeable apical layer that protects against the external environment. This function is conserved in vertebrates and invertebrates, despite the differing molecular composition of the protective barrier. Epithelial cells also have junctions that create a paracellular diffusion barrier (tight or septate junctions). To...
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