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A reliable, high-resolution and high-throughput genotyping method for HLA-DRB1.

Human immunology - 1 Jun 2015

Yang Fan, Jiang Fuman, Chai Xianghua, Guo Yulai, Lan Zhiheng, Yuan Yuying, Huang Changjian, Zhu Zhongyi, Li Huiling, Du Bole, Wang Jun, Zhou Lijun, Chen Zhonglin, Yang Ling, Zhou Meizhen, Zeng Hao, Xu Yicou, Wang Wei

Abstract excerpt

Human leukocyte antigen (HLA) DNA typing is an essential part to identify a donor who may be a good match for the patients who need haematopoietic stem cells from bone marrow. Thus, fetching quickly high-resolution genotype is very important at present. However, current HLA DNA typing methods especially for HLA-DRB1 generally yielded ambiguous typing results because of high degree of heterozygosity on exome...

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PMID: 25890007
DOI: 10.1016/j.humimm.2015.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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