Article
Association of human leukocyte antigen with interstitial lung disease in rheumatoid arthritis: a protective role for shared epitope.
PloS one - 1 Jan 2012
Furukawa Hiroshi, Oka Shomi, Shimada Kota, Sugii Shoji, Ohashi Jun, Matsui Toshihiro, Ikenaka Tatsuoh, Nakayama Hisanori, Hashimoto Atsushi, Takaoka Hirokazu, Arinuma Yoshiyuki, Okazaki Yuko, Futami Hidekazu, Komiya Akiko, Fukui Naoshi, Nakamura Tadashi, Migita Kiyoshi, Suda Akiko, Nagaoka Shouhei, Tsuchiya Naoyuki, Tohma Shigeto
Abstract excerpt
INTRODUCTION: Interstitial Lung Disease (ILD) is frequently associated with Rheumatoid Arthritis (RA) as one of extra-articular manifestations. Many studies for Human Leukocyte Antigen (HLA) allelic association with RA have been reported, but few have been validated in an RA subpopulation with ILD. In this study, we investigated the association of HLA class II alleles with ILD in RA. METHODS: An association study...
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