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Article

Polymorphisms of STAT6 and specific serum IgE levels in patients with penicillin allergy.

International journal of clinical pharmacology and therapeutics - 1 Jul 2012

Huang Chen-Zheng, Zou Dan, Yang Jing, Qiao Hai-Ling

Abstract excerpt

OBJECTIVE: Signal transducer and activator of transcription (STAT) 6 signaling pathway is required for mediating the biologic functions of interleukin (IL)-4 which is proved to play an important role in the pathogenesis of allergic diseases and the induction of specific immunoglobulin (Ig) E synthesis. The current studies are conducted to evaluate the relationship between polymorphisms of STAT6, specific IgE and...

Read the complete abstract on PubMed

Topics

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Share to Adolescent
Share to Drug Hypersensitivity
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin E

Share to Penicillins

Share to Polymorphism, Single Nucleotide

Share to STAT6 Transcription Factor

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Source

Identifiers

PMID: 22578203
DOI: 10.5414/CP201691

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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