Article
HLA-DRB genotype and specific IgE responses in patients with allergies to penicillins.
Chinese medical journal - 20 Mar 2006
Yang Jing, Qiao Hai-ling, Zhang Yue-wen, Jia Lin-jing, Tian Xin, Gao Na
Abstract excerpt
BACKGROUND: Because of the pivotal role of the human leukocyte antigen (HLA) class II molecules in regulating the immune response and their extensive polymorphism, it is not surprising that particular HLA class II alleles have been implicated in susceptibility to allergic diseases and in restriction of the IgE responses to a variety of allergens. We investigated the relationship between HLA-DRB genotype and...
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