Article
Interleukin-18 and IL18 -607A/C and -137G/C gene polymorphisms in patients with penicillin allergy.
The Journal of international medical research - 1 Jan 2011
Ming L, Wen Q, Qiao H-L, Dong Z-M
Abstract excerpt
This study investigated the association between polymorphisms (-607A/C and -137G/C) in the promoter region of the IL18 gene (which encodes interleukin [IL]-18) and serum levels of IL-18, using standard genotyping techniques (sequence specific primer-polymerase chain reaction) and an enzyme-linked immunosorbent assay, respectively, in patients allergic to penicillin. A higher frequency of A alleles and the AA...
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