Article
Comprehensive analysis for viral elements and interleukin-28B polymorphisms in response to pegylated interferon plus ribavirin therapy in hepatitis C virus 1B infection.
Hepatology (Baltimore, Md.) - 1 Nov 2012
Maekawa Shinya, Sakamoto Minoru, Miura Mika, Kadokura Makoto, Sueki Ryota, Komase Kazuki, Shindo Hiroko, Komatsu Nobutoshi, Shindo Kuniaki, Kanayama Asuka, Ohmori Takako, Amemiya Fumitake, Takano Shinichi, Yamaguchi Tatsuya, Nakayama Yasuhiro, Kitamura Takatoshi, Inoue Taisuke, Okada Shunichi, Enomoto Nobuyuki
Abstract excerpt
UNLABELLED: To comprehensively characterize the contribution of virological factors as well as interleukin-28B (IL28B) single-nucleotide polymorphisms (SNPs) in determining treatment responses in pegylated-interferon plus ribavirin (Peg-IFN/RBV) therapy for chronic hepatitis C virus (HCV)-1b infection, we undertook a retrospective cohort analysis for the pretreatment dominant complete HCV open reading frame (ORF)...
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