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Article

IL28B rs12980275 and HLA rs4273729 genotypes as a powerful predictor factor for rapid, early, and sustained virologic response in patients with chronic hepatitis C.

Archives of virology - 1 Jan 2017

Sedighimehr Parvaneh, Irani Shiva, Sakhaee Fatemeh, Vaziri Farzam, Aghasadeghi Mohammadreza, Sadat Seyed Mehdi, Jamnani Fatemeh Rahimi, Fateh Abolfazl, Siadat Seyed Davar

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) in the Interleukin-28B (IL28B) gene and rs4273729 in the human leukocyte antigen (HLA) gene in chronic hepatitis C (CHC) virus infection are important for predicting treatment outcome. In this study, the distribution of IL28B SNPs (rs12979860 and rs12980275) and HLA rs4273729 in rapid virologic response (RVR), complete early virologic response (cEVR) and sustained virologic...

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PMID: 27714501
DOI: 10.1007/s00705-016-3095-1

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