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Article

Association study of a common variant near IRS1 with type 2 diabetes mellitus in Chinese Han population.

Endocrine - 1 Feb 2013

Tang Yong, Han Xueyao, Sun Xiuqin, Lv Chao, Zhang Xiaomei, Guo Wulan, Ren Qian, Luo Yingying, Zhang Xiuying, Zhou Xianghai, Ji Linong

Abstract excerpt

The insulin receptor substrate-1 (IRS1) plays an important role in insulin signaling. A recent genome-wide association study identified rs2943641C>T as a susceptibility locus for type 2 diabetes mellitus (T2DM) in Caucasian patients. Therefore, we determined whether this common variant near IRS1 is also associated with the risk of T2DM and T2DM-related phenotypes in a Chinese Han population. A total of 2,290...

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Source

Identifiers

PMID: 22576021
DOI: 10.1007/s12020-012-9693-0

Genes

IRS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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