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Article

Evidence of association between single-nucleotide polymorphisms in lipid metabolism-related genes and type 2 diabetes mellitus in a Chinese population.

International journal of medical sciences - 1 Jan 2021

Li Yiping, He Siqi, Li Chuanyin, Shen Keyu, Yang Man, Tao Wenyu, Yang Ying, Shi Li, Yao Yufeng

Abstract excerpt

Background: Type 2 diabetes mellitus (T2DM) is a complex chronic metabolic disorder triggered by insulin resistance in peripheral tissues. Evidence has shown that lipid metabolism and related genetic factors lead to insulin resistance. Hence, it is meaningful to investigate the association between single-nucleotide polymorphisms (SNPs) in lipid metabolism-related genes and T2DM. Methods: A total of 1,194 subjects...

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Identifiers

PMID: 33390804
DOI: 10.7150/ijms.53004
PMCID: PMC7757135

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