Variant Philadelphia translocations in chronic myeloid leukemia: correlation with cancer breakpoints, fragile sites and oncogenes.

doi:10.1016/0304-3835(90)90126-i

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Article

Variant Philadelphia translocations in chronic myeloid leukemia: correlation with cancer breakpoints, fragile sites and oncogenes.

Cancer letters - 17 Dec 1990

Stopera S A, Ray M, Riordan D, Christie N, Wickstrom D

Abstract excerpt

Four cases of variant Philadelphia (Ph1) translocations were found in 72 patients (5.5%) with Ph1-positive chronic myeloid leukemia (CML). One previously unreported case was a simple variant translocation, namely, 46,XY,t(11;17)(q13;p13),t(17;22)(q25;q22); 46,XY,t(1;21)(q32;q11),t(11;17)(q13;p13)...

Topics

Genetic Variation
Humans
Karyotyping
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Oncogenes
Philadelphia Chromosome
Translocation, Genetic

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