Article
Additional t(11;17)(q23;q21) in a patient with Philadelphia-positive mixed lineage antigen-expressing leukemia.
Cancer genetics and cytogenetics - 1 Apr 2001
Nishii K, Usui E, Sakakura M, Miyata E, Ridge S A, Ford A M, Masuya M, Chen F, Mitani H, Yamaguchi M, Katayama N, Kita K, Shiku H
Abstract excerpt
We describe very uncommon phenotypic and cytogenetic findings in a 40-year-old female with blast phase of Philadelphia chromosome (Ph)-positive CML. In addition to the t(9;22)(q34;q11) that was detected in all metaphases, a t(11;17)(q23;q21) was identified in 15 of 20 metaphases. Reverse transcription-polymerase chain reaction showed the major and minor bcr/abl fusion transcripts in the cells from a bone marrow...
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