Article
A variant Philadelphia chromosome (Ph1) positive chronic myelocytic leukemia.
Acta medica Okayama - 1 Oct 1990
Haruta Y, Takahashi I, Sekito N, Miyamoto K, Shimamoto M, Wakita Y, Kikkawa K, Nakamura T, Seto T, Yamashita J
Abstract excerpt
A rare case of variant Philadelphia (Ph1) chromosome positive [46, XX, t (9; 22) (q34; q11), inv (9) (9q22; 22q13)] chronic myelocytic leukemia (CML) was described. The patient, 73 years old female, was hospitalized to our hospital because of leukocytosis. Hematological findings corresponded to those of CMLs. However, this case lacked hepatosplenomegaly. Southern blot analysis using a 3 breakpoint cluster region...
Topics
- Aged
- Female
- Gene Rearrangement
- Genetic Variation
- Humans
- Karyotyping
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Philadelphia Chromosome
- Translocation, Genetic