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Article

Towards Next-Generation Sequencing for HIV-1 Drug Resistance Testing in a Clinical Setting.

Viruses - 7 Oct 2022

Teo Calesta Hui Yi, Norhisham Nurul Hannah Binte, Lee Ogestelli Fabia, Png Siyu, Chai Chean Nee, Yan Gabriel, Tang Julian Wei-Tze, Lee Chun Kiat

Abstract excerpt

The HIV genotypic resistance test (GRT) is a standard of care for the clinical management of HIV/AIDS patients. In recent decades, population or Sanger sequencing has been the foundation for drug resistance monitoring in clinical settings. However, the advent of high-throughput or next-generation sequencing has caused a paradigm shift towards the detection and characterization of low-abundance covert mutations...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36298763
DOI: 10.3390/v14102208
PMCID: PMC9608942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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