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Article

Standardization and statistical approaches to therapeutic trials in the R6/2 mouse.

Brain research bulletin - 30 Sept 2003

Hockly Emma, Woodman Benjamin, Mahal Amarbirpal, Lewis Cathryn M, Bates Gillian

Abstract excerpt

The R6/2 mouse is the most widely used animal model of Huntington's disease (HD), a genetic disorder causing movement disorders, personality changes, dementia, and premature death, for which there is currently no effective therapy. Use of animal models to assess novel therapeutic approaches to HD...

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PMID: 13679245
DOI: 10.1016/s0361-9230(03)00185-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-13679245-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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