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Article

PNA HyBeacons for analysis of human mutations related to statin-induced myopathy.

Artificial DNA, PNA & XNA - 1 Jan 2000

Gale Nittaya, Kocalka Petr, Mardle Charlotte, Brown Tom

Abstract excerpt

Aminoalkyl and alkyne-tagged PNA HyBeacons have been synthesized, labeled with fluorescein via conventional amide bond or triazole formation (click chemistry) and used to detect single nucleotide polymorphisms (SNPs) implicated in statin-induced myopathy. The PNA HyBeacons gave much better mismat...

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Identifiers

PMID: 22567191
DOI: 10.4161/adna.18179
PMCID: PMC3324338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22567191-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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