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Article

Sensitive detection of single-nucleotide polymorphisms by conjugated polymers for personalized treatment of hypertension.

Science translational medicine - 8 Mar 2023

Shen Qi, Zhang Honghong, Huang Yiming, Li Mingyu, Zhao Hao, Yang Zhiwen, Zhao Haijing, Liu Qi, Fu Zihao, Di Yufei, Liu Libing, Bai Haotian, Lv Fengting, Chen Yundai, Liu Yuqi, Wang Shu

Abstract excerpt

Genetic variants among individuals have been associated with ineffective control of hypertension. Previous work has shown that hypertension has a polygenic nature, and interactions between these loci have been associated with variations in drug response. Rapid detection of multiple genetic loci with high sensitivity and specificity is needed for the effective implementation of personalized medicine for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36888697
DOI: 10.1126/scitranslmed.abq5753

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