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Article

Increased late sodium current contributes to long QT-related arrhythmia susceptibility in female mice.

Cardiovascular research - 1 Aug 2012

Lowe John S, Stroud Dina Myers, Yang Tao, Hall Lynn, Atack Thomas C, Roden Dan M

Abstract excerpt

AIMS: Female gender is a risk factor for long QT-related arrhythmias, but the underlying mechanisms remain uncertain. Here, we tested the hypothesis that gender-dependent function of the post-depolarization 'late' sodium current (I(Na-L)) contributes. METHODS AND RESULTS: Studies were conducted i...

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Identifiers

PMID: 22562703
DOI: 10.1093/cvr/cvs160
PMCID: PMC3633400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22562703-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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