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Article

NK cells are not required for spontaneous autoimmune diabetes in NOD mice.

PloS one - 1 Jan 2012

Beilke Joshua N, Meagher Craig T, Hosiawa Karoline, Champsaur Marine, Bluestone Jeffrey A, Lanier Lewis L

Abstract excerpt

NK cells have been shown to either promote or protect from autoimmune diseases. Several studies have examined the role of receptors preferentially expressed by NK cells in the spontaneous disease of NOD mice or the direct role of NK cells in acute induced disease models of diabetes. Yet, the role of NK cells in spontaneous diabetes has not been directly addressed. Here, we used the NOD.NK1.1 congenic mouse model...

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Share to Cell Membrane
Share to Cytotoxicity, Immunologic
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Killer Cells, Natural

Share to Lymphocyte Activation

Share to Mice, Inbred NOD

Share to Pancreas

Source

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Identifiers

PMID: 22558306
DOI: 10.1371/journal.pone.0036011
PMCID: PMC3338490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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