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Article

Involvement of PTPN5, the gene encoding the striatal-enriched protein tyrosine phosphatase, in schizophrenia and cognition.

Psychiatric genetics - 1 Aug 2012

Pelov Ilana, Teltsh Omri, Greenbaum Lior, Rigbi Amihai, Kanyas-Sarner Kyra, Lerer Bernard, Lombroso Paul, Kohn Yoav

Abstract excerpt

OBJECTIVE: Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific member of the protein tyrosine phosphatase (PTP) family that has been implicated in learning and memory. In this study, we examined the association of the protein tyrosine phosphatase non-receptor 5 (PTPN5) gene, which encodes for STEP, with both schizophrenia and cognitive functioning in the Israeli Jewish population. METHODS: A...

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Identifiers

PMID: 22555153
DOI: 10.1097/YPG.0b013e3283518586
PMCID: PMC3760343

Genes

PTPN5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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