Article
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function.
Journal of psychiatric research - 1 Feb 2012
LeBlanc Marissa, Kulle Bettina, Sundet Kjetil, Agartz Ingrid, Melle Ingrid, Djurovic Srdjan, Frigessi Arnoldo, Andreassen Ole A
Abstract excerpt
BACKGROUND: Several aspects of neurocognitive function have high heritability, but the molecular genetic mechanisms underlying neurocognition are not known. We performed a genome-wide association study (GWAS) to identify genes associated with neurocognition. METHODS: 700 Subjects (schizophrenia spectrum disorder, n=190, bipolar disorder n=157 and healthy individuals n=353) were tested with an extensive...
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