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Article

The SNAP-25 gene is associated with cognitive ability: evidence from a family-based study in two independent Dutch cohorts.

Molecular psychiatry - 1 Sept 2006

Gosso M F, de Geus E J C, van Belzen M J, Polderman T J C, Heutink P, Boomsma D I, Posthuma D

Abstract excerpt

The synaptosomal-associated protein of 25 kDa (SNAP-25) gene plays an integral role in synaptic transmission, and is differentially expressed in the mammalian brain in the neocortex, hippocampus, anterior thalamic nuclei, substantia nigra and cerebellar granular cells. Recent studies have suggested a possible involvement of SNAP-25 in learning and memory, both of which are key components of human intelligence. In...

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PMID: 16801949
DOI: 10.1038/sj.mp.4001868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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