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Article

Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis.

Scandinavian journal of gastroenterology - 1 Jul 2012

Srivastava Brijesh, Mells George F, Cordell Heather J, Muriithi Agnes, Brown Matthew, Ellinghaus Eva, Franke Andre, Karlsen Tom H, Sandford Richard N, Alexander Graeme J, Chapman Roger W, Rushbrook Simon M, Melum Espen

Abstract excerpt

BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammation and fibrosis of the bile ducts eventually leading to biliary cirrhosis. Recent genetic studies in PSC have identified associations at 2q13, 2q35, 3p21, 4q27, 13q31 and suggestive association at 10p15. The aim of this study was to further characterize and refine the genetic...

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Identifiers

PMID: 22554193
DOI: 10.3109/00365521.2012.682090

Genes

MST1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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