Article
CD20+ tumor-infiltrating lymphocytes have an atypical CD27- memory phenotype and together with CD8+ T cells promote favorable prognosis in ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2012
Nielsen Julie S, Sahota Rob A, Milne Katy, Kost Sara E, Nesslinger Nancy J, Watson Peter H, Nelson Brad H
Abstract excerpt
PURPOSE: Tumor-infiltrating lymphocytes (TIL), in particular CD8(+) T cells and CD20(+) B cells, are strongly associated with survival in ovarian cancer and other carcinomas. Although CD8(+) TIL can mediate direct cytolytic activity against tumors, the role of CD20(+) TIL is poorly understood. He...
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