Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA recombination and natural selection pressure sustain genetic sequence diversity of the feline MHC class I genes.

The Journal of experimental medicine - 1 Aug 1990

Yuhki N, O'Brien S J

Abstract excerpt

Sequence comparisons of seven distinct MHC class I cDNA clones revealed that feline class I molecules have a remarkable similarity to human HLA genes in their organization of functional domains as well as in the nonrandom partitioning of genetic variability according to the functional constraints ascribed to different regions of the MHC molecule. The distribution of the pattern of sequence polymorphism in the cat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Protein Conformation

Share to Sequence Homology, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 1695669
DOI: 10.1084/jem.172.2.621
PMCID: PMC2188339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA recombination and natural selection pressure sustain genetic sequence diversity of the feline MHC class I genes.PMID 1695669Read ↗

Exchanges of short polymorphic DNA segments predating speciation in feline major histocompatibility complex class I genes.Semantic proximity Read ↗

Polymorphisms and tissue expression of the feline leukocyte antigen class I loci FLAI-E, FLAI-H, and FLAI-K.Semantic proximity Read ↗

Sequences, annotation and single nucleotide polymorphism of the major histocompatibility complex in the domestic cat.Semantic proximity Read ↗

Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.Semantic proximity Read ↗

DNA variation of the mammalian major histocompatibility complex reflects genomic diversity and population history.Semantic proximity Read ↗

High-resolution characterization of the structural features and genetic variation of six feline leukocyte antigen class I loci via single molecule, real-time (SMRT) sequencing.Semantic proximity Read ↗

Evolution of MHC class I genes in higher primates.Semantic proximity Read ↗

The role of the Major Histocompatibility Complex in the spread of contagious cancers.Semantic proximity Read ↗

Characterization of both major histocompatibility complex classes in a wild social mammal: the banded mongooseSemantic proximity Read ↗

Genetic divergence of the rhesus macaque major histocompatibility complex.Semantic proximity Read ↗

Recombination and mutation shape variations in the major histocompatibility complex.Semantic proximity Read ↗

Natural selection and the diversification of vertebrate immune effectors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.