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Article

Spatiotemporal adaptive evolution of an MHC immune gene in a frog-fungus disease system.

Heredity - 1 Apr 2021

Trujillo Alexa L, Hoffman Eric A, Becker C Guilherme, Savage Anna E

Abstract excerpt

Genetic diversity of major histocompatibility complex (MHC) genes is linked to reduced pathogen susceptibility in amphibians, but few studies also examine broad spatial and temporal patterns of MHC and neutral genetic diversity. Here, we characterized range-wide MHC diversity in the Northern leopard frog, Rana pipiens, a species found throughout North America that is experiencing disease-related declines. We used...

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Identifiers

PMID: 33510466
DOI: 10.1038/s41437-020-00402-9
PMCID: PMC8115231

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