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Article

Selection and recombination drive the evolution of MHC class II DRB diversity in ungulates.

Heredity - 1 Dec 2006

Schaschl H, Wandeler P, Suchentrunk F, Obexer-Ruff G, Goodman S J

Abstract excerpt

Major histocompatibility complex (MHC) antigen-presenting genes are the most variable loci in vertebrate genomes. Host-parasite co-evolution is assumed to maintain the excessive polymorphism in the MHC loci. However, the molecular mechanisms underlying the striking diversity in the MHC remain contentious. The extent to which recombination contributes to the diversity at MHC loci in natural populations is still...

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PMID: 16941019
DOI: 10.1038/sj.hdy.6800892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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