Article
Association between CASP7 and CASP14 genetic polymorphisms and the risk of childhood leukemia.
Human immunology - 1 Jul 2012
Park Chulbum, Han Sohee, Lee Kyoung-Mu, Choi Ji-Yeob, Song Nan, Jeon Sujee, Park Sue K, Ahn Hyo Seop, Shin Hee Young, Kang Hyoung Jin, Koo Hong Hoe, Seo Jong Jin, Choi Ji Eun, Kang Daehee
Abstract excerpt
Current evidence suggests that apoptosis and the cell cycle system play an important role in cancer development. To identify susceptible genetic markers in these mechanisms, we did an association study in 63 patients and 148 controls. A total of 304 SNPs in 31 gene regions were selected. We evaluated an association at a gene region level by computing the minimum P-value (minP) and doing the false discovery rate...
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