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Article

Polymorphisms in the CASP8 gene and the risk of epithelial ovarian cancer.

Gynecologic oncology - 1 Sept 2011

Ma Xiangdong, Zhang Jianfang, Liu Shujuan, Huang Yanhong, Chen Biliang, Wang Detang

Abstract excerpt

OBJECTIVE: The CASP8 gene plays a central role in the apoptotic pathway and is therefore a plausible cancer susceptibility gene. However, the precise role of the CASP8 gene in epithelial ovarian cancer carcinogenesis is unclear. Therefore, we analyzed the correlation between single nucleotide polymorphisms (SNPs) and haplotypes in CASP8 and the risk and clinical characteristics of epithelial ovarian cancer (EOC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21714991
DOI: 10.1016/j.ygyno.2011.05.031

Genes

CASP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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