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Article

Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer.

BMC medical genomics - 30 Apr 2012

Lavender Nicole A, Rogers Erica N, Yeyeodu Susan, Rudd James, Hu Ting, Zhang Jie, Brock Guy N, Kimbro Kevin S, Moore Jason H, Hein David W, Kidd La Creis R

Abstract excerpt

BACKGROUND: Molecular and epidemiological evidence demonstrate that altered gene expression and single nucleotide polymorphisms in the apoptotic pathway are linked to many cancers. Yet, few studies emphasize the interaction of variant apoptotic genes and their joint modifying effects on prostate cancer (PCA) outcomes. An exhaustive assessment of all the possible two-, three- and four-way gene-gene interactions is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22546513
DOI: 10.1186/1755-8794-5-11
PMCID: PMC3355002

Genes

AKT3
PRKCQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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