Article
Analysis of Tp53 codon 72 polymorphisms, Tp53 mutations, and HPV infection in cutaneous squamous cell carcinomas.
PloS one - 1 Jan 2012
Loeb Keith R, Asgari Maryam M, Hawes Stephen E, Feng Qinghua, Stern Joshua E, Jiang Mingjun, Argenyi Zsolt B, de Villiers Ethel-Michele, Kiviat Nancy B
Abstract excerpt
BACKGROUND: Non-melanoma skin cancers are one of the most common human malignancies accounting for 2-3% of tumors in the US and represent a significant health burden. Epidemiology studies have implicated Tp53 mutations triggered by UV exposure, and human papilloma virus (HPV) infection to be significant causes of non-melanoma skin cancer. However, the relationship between Tp53 and cutaneous HPV infection is not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.