Article
[Relationship between V617F mutation and 46/1 haplotype in JAK2 gene in patients with chronic myeloproliferative diseases and frequencies of 46/1 haplotype in different Chinese nationalities].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2012
Tian Zheng-Qin, Zhu Ping, Liu Hong-Xing, Chen Yan, Wang Fang, Zhang Yang, Teng Wen, Gong Yi-Wen, Xia Jun-Yan, Bai De-Cheng, Liu Qian, Wu Xue-Qiang
Abstract excerpt
Somatic gene V617F mutation in JAK2 is a critical molecular and biological indicator to diagnosis of chronic myeloproliferative disease (MPD). This study was aimed to investigate the genetic background of V617F mutation in 46/1 gene haplotype in Chinese MPD patients, and the frequencies of 46/1 gene haplotype and V617F mutation in three nationalities of Chinese populations. Peripheral blood or bone marrow samples...
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