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Article

Contributions of aryl hydrocarbon receptor genetic variants to the risk of glioma and PAH-DNA adducts.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Aug 2012

Gu Aihua, Ji Guixiang, Jiang Tao, Lu Ailin, You Yongping, Liu Ning, Luo Chengzhang, Yan Wei, Zhao Peng

Abstract excerpt

The aryl hydrocarbon receptor (AHR) gene is involved in the response to polycyclic aromatic hydrocarbon (PAH) exposure. To investigate the hypothesis that the genetic variants in the AHR gene might be a causal genetic susceptibility to PAH-DNA adduct formation and glioma risk, we conducted a case-control study of 384 glioma cases and 384 cancer-free controls to explore the association between six common...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22539616
DOI: 10.1093/toxsci/kfs158

Genes

PAH
AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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