Article
[Association of the IL-18 gene polymorphism with susceptibility to colorectal cancer].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 1 Apr 2012
Guo Jun-yu, Qin An-qiang, Li Ru-kun, Yang Chang-mou, Huang Fu-da, Huang Zhan-yi, Guo Hou-ji
Abstract excerpt
OBJECTIVE: To investigate single nucleotide polymorphisms(SNPs) and haplotypes of interleukin-18(IL-18) gene associated with the susceptibility to colorectal cancer(CRC). METHODS: Two SNPs of IL-18 gene promoter -137G/C and -607C/A in 170 patients with CRC and 160 healthy controls matched by age and sex in a Chinese population were analyzed using polymerase chain reaction-restriction fragment length...
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