Article
IL-18 serum level and IL-18 promoter gene polymorphism in Iranian patients with gastrointestinal cancers.
Journal of gastroenterology and hepatology - 1 Jun 2009
Haghshenas Mohammad Reza, Hosseini Seyed Vahid, Mahmoudi Mahmoud, Saberi-Firozi Mehdi, Farjadian Shirin, Ghaderi Abbas
Abstract excerpt
BACKGROUND AND AIM: Interleukin (IL)-18 level and association of its two promoter gene polymorphisms at -607 C/A and -137 G/C positions were investigated in Iranian patients with gastrointestinal (GI) cancers. METHODS: 232 cases of GI cancers and 312 healthy controls were enrolled. Serum level of IL-18 was measured by enzyme linked immunosorbent assay (ELISA) and genotyping of IL-18 gene polymorphisms were...
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