Article
Modeling Parkinson's disease using induced pluripotent stem cells.
Current neurology and neuroscience reports - 1 Jun 2012
Byers Blake, Lee Hsiao-lu, Reijo Pera Renee
Abstract excerpt
Our understanding of the underlying molecular mechanism of Parkinson's disease (PD) is hampered by a lack of access to affected human dopaminergic (DA) neurons on which to base experimental research. Fortunately, the recent development of a PD disease model using induced pluripotent stem cells (iPSCs) provides access to cell types that were previously unobtainable in sufficient quantity or quality, and presents...
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