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Article

Using induced pluripotent stem cells for modeling Parkinson’s disease

23 Sept 2019

Abstract excerpt

Parkinson's disease (PD) is an age-related neurodegenerative disease caused by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. As DA neurons degenerate, PD patients gradually lose their ability of movement. To date no effective therapies are available for the treatment of PD and its pathogenesis remains unknown. Experimental models that appropriately mimic the development of PD are...

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PMID: 31616540
DOI: 10.4252/wjsc.v11.i9.634

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