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Article

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress.

PloS one - 1 Jan 2011

Byers Blake, Cord Branden, Nguyen Ha Nam, Schüle Birgitt, Fenno Lief, Lee Patrick C, Deisseroth Karl, Langston J William, Pera Renee Reijo, Palmer Theo D

Abstract excerpt

Parkinson's disease (PD) is an incurable age-related neurodegenerative disorder affecting both the central and peripheral nervous systems. Although common, the etiology of PD remains poorly understood. Genetic studies infer that the disease results from a complex interaction between genetics and environment and there is growing evidence that PD may represent a constellation of diseases with overlapping yet...

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Source

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Identifiers

PMID: 22110584
DOI: 10.1371/journal.pone.0026159
PMCID: PMC3217921

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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