Article
CRYAB-650 C>G (rs2234702) affects susceptibility to Type 1 diabetes and IAA-positivity in Swedish population.
Human immunology - 1 Jul 2012
Sun Chengjun, Sedimbi Saikiran K, Ashok Ayyappa K, Sanjeevi Carani B
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. CRYAB gene, which encodes alpha B-crystallin (a member of small heat shock protein), was reported as a potential autoimmune target. In this study we investigated whether SNPs in the promoter region of CRYAB gene were also important in the etiology of Type 1 diabetes (T1D)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
